Isagenix Review: Is This Diet Safe For Weight Loss? (2024)

• The 30-Day Reset program alternates between shake days (where shakes replace most meals) and cleanse days, where participants replace most meals with supplements.
• 30-Day Reset costs between $320 to $426.
• Experts say the 30-Day Reset may not be sustainable for long-term weight loss.

This review focuses on Isagenix’s 30-Day Reset. The company’s other weight loss kits may have slightly different methods. According to an Isagenix representative, the main goal of the program is weight loss, but some customers also follow the program for detoxification purposes; the amount of weight a person can expect to lose varies between individuals.

When following Isagenix’s 30-Day Reset, individuals alternate between a series of “Shake Days” and “Cleanse Days.”

During a shake day, participants replace a morning and afternoon meal with an Isa-lean shake, a whey- or plant-based protein shake containing 24 grams of protein with added vitamins and plant-based enzymes. Participants also eat one 400 to 600-calorie meal, which they make themselves. Shake days also include various other supplements, like Ionix Supreme, a drink mix containing adaptogens like ashwagandha, eleuthero and rhodiola among others.

On cleanse days, participants replace all meals with “Cleanse for Life,” a drink mix containing plant compounds like turmeric, aloe vera and peppermint. The drink is designed to “support the body’s natural detoxification process and help fight oxidative stress,” according to the company. Participants also consume one to two “snack bites,” which are 100-110-calorie snacks containing 5 grams of plant-based protein, and other Isagenix supplements.

The Isagenix 30-Day Reset program can be purchased directly from the company’s website. It costs $426 to check out as a guest, but customers can sign up for a preferred membership to purchase it for $363. Isagenix also offers a subscription service, which provides the 30-Day Reset for $320 to be delivered at repeated intervals, such as every 30, 60 or 90 days.

By default, the kit includes the following:

• IsaLean Shake Creamy Dutch Chocolate: Two canisters
• IsaLean Shake Creamy French Vanilla: Two canisters
• Cleanse for Life Natural Rich Berry: Two canisters
• Ionix Supreme Natural Fruit Flavor: One 32 oz bottle
• Peanut Butter Bliss Snack Bites: One eight-count box
• IsaFlush: 60 capsules
• Natural Accelerator: 60 capsules

Customers can choose which products they’d like in their 30-Day Reset kit in different categories. For instance, they can select a plant-based alternative to the whey-based IsaLean Shake or decide between different flavors, like chocolate or birthday cake. They can also swap the Ionix Supreme drink mix for the Adaptogen Elixer, a kombucha black tea enhanced with adaptogens and herbs.

Additionally, customers can also purchase products from Isagenix Independent Associates—individuals who sell Isagenix products via the company’s multi-level marketing (MLM) structure. Product prices may vary between individuals.

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Day 1 of the Isagenix 9 day Cleanse! - The Wellness Center

“Isagenix isn’t something that I or most registered dietitians I know would ever recommend,” says Maddie Pasquariello, a registered dietitian in Brooklyn, New York. For instance, she says that the 30-day Reset’s use of cleanse days could potentially encourage unhealthy or disordered eating habits rather than supporting long-term lifestyle changes. “If your internal organs are in working order, you don’t need a detox or cleanse to support your health goals,” she explains.

While Pasquariello notes that the IsaLean shake appears to have adequate nutrition and would likely provide some micronutrient benefits, it also contains sugar and other additives, such as flavorings. Additionally, Pasquariello points out that a single serving of the shake contains more than 50% of the recommended daily value for some nutrients, such as vitamin B6, B12 and manganese, which may be of concern since the 30-Day Reset recommends drinking multiple servings on shake days.

“It doesn’t appear that any of the micronutrient quantities listed would verge into toxic levels, even if you did drink more than one shake per day, but it’s something to consider,” she says.

A Look At Isagenix’s Cited Research

Isagenix has a small body of research on its website supporting certain claims for its products.

For example, one very small 2022 study divided 20 participants with overweight or obesity into two groups. One group fasted one day per week, the other two days per week. On fast days, both groups consumed around 400 calories. On food days, participants consumed a diet of 1,500 calories for women and 1,850 calories for men. Both groups consumed Isagenix products and whole foods to meet their daily caloric and nutrition requirements. After a four-week period, both groups experienced lower body weights, body fat percentages and blood sugar levels. But the two fast day per-week group lost slightly more weight overall.^[1]Arciero PJ, Arciero KM, Poe M et al. Intermittent fasting two days versus one day per week, matched for total energy intake and expenditure, increases weight loss in overweight/obese men and women. Nutrition Journal. 2022:21, 36.

“The study findings suggest that, if anything, results are largely attributed to various intermittent fasting protocols or caloric restriction,” Pasquellario explains. “Even if you are practicing intermittent fasting under the supervision of an RD and medical team, you don’t need this product lineup to do so.”

What’s more, Pasquariello notes that some of the studies listed on Isagenix’s website (such as the one featured above) have small sample sizes and at least one conflict of interest. For instance, they are either funded directly by Isagenix or conducted by professionals who work as consultants with Isagenix. “This isn’t what I hope to see if I’m seeking gold-standard research about a particular nutrient or ingredient,” explains Pasquariello.

Isagenix’s 30-Day Reset has mostly positive reviews on the company’s website. Reviewers generally find the program easy to follow, with some reporting weight loss results and other effects, such as higher energy levels. However, some negative reviews state individuals felt hungry throughout the day without seeing their desired weight loss results. Others found the cost too expensive.

Isagenix has an A+ rating with the Better Business Bureau (BBB) and an average rating of 3.4 out of 5 stars. One five-star review touts excellent customer service, while a one-star review notes that they were locked out of their account. The BBB received nine complaints in the last three years, most of which have been resolved.